Villain with U

• Ultron

  Marvel supervillain; killer AI vs the Avengers.

• Ursula

  Sea witch from The Little Mermaid; classic baddie.

• Undertaker

  WWE character who often played the bad guy.

• Umbridge

  Dolores Umbridge from Harry Potter, cruel headmistress.

• Underminer

  Villain from The Incredibles; drills up from underground.

• Uma

  Disney Descendants villain; captain of a pirate crew.

• Umbrella Man
• Unicron

  Transformers foe; planet‑eating cosmic entity.

• Undyne

  Fish-like heroine to many, but a ruthless villain in early Undertale routes.

• Unabomber

  Domestic terrorist Ted Kaczynski, the Unabomber.

• Ulik

  Rock troll villain from Marvel’s Thor comics.

• ubu

  Ubu Roi by Jarry, grotesque tyrant antihero.

• Uchiha Madara

  Main antagonist of Naruto, seeks Infinite Tsukuyomi

• Urgot

  League of Legends juggernaut villain from Zaun

• Ugandan Knuckles

  Meme villain version of Knuckles, from VRChat lore

The words in the list Villain with U come from players of the word game Categories game.