Villain with S
- Scar
- Sandman
- Satan
- Scarecrow
- Sauron
- Sinestro
- Scarface
- Slenderman
- Salazar Slytherin
- Scorpion
- Skeletor
- Shigaraki
- Stalin
- silver surfer
- Sand man
- Advertisement
- Slade
- Shego
- Slender man
- Shredder
- Scrooge
- Sith
- Saruman
- Snoke
- swiper
- Sid
- sand man
- scarlet witch
- satin
- Sidious
- Scream
- Severus snape
- Shadow
- Sephiroth
- Sabretooth
- Slitherin
- Spawn
- scarlett witch
- scorpio
- stepmother
- Sasquatch
- sinister
- scaramanga
- sinister six
- serpent
- snakes
- Storm
- Son of Sam
- Snidely Whiplash
- sindrome
- sinbad
- Snake
- sal
- Scrappy Doo
- scar from lion king
- Sorcerer
- Subzero
- Syndrom
- Savitar
- Spider
- Step mother
- Advertisement
- scar face
- spongebob
- Stromberg
- Snake man
- surtur
- Solomon Grundy
- Starscream
- Spider-Man
- sarah
- Sinistro
- shark
- Stingray
- Stain
- snow queen
- Smeagol
- Smaug
- Sara
- Sun
- superman's enemy
- Shylock
- Spy
- Storm trooper
- Strange
- Sabertooth
- snakeman
- Shere Khan
- sabertooth
- Samson
- samba
- susan
- shocker
- Samara
- Spot
- Sambha
- Stinky Pete
- Sarah Palin
- Sentinel
- Siren
- Silas
- Signora
The words in the list Villain with S come from players of the word game Categories game.