Villain with O
- Ogre
- Otto Octavius
- Octavious
- Osama bin laden
- Octavius
- Odin
- Overlord
- Omni man
- Omega
- Omniman
- Oblivion
- Orochimaru
- OJ Simpson
- onceler
- Ozymandias
- Advertisement
- Otto
- Orion
- Orc
- Obito
- Oliver
- osborn
- Osborne
- Osama
- Ozai
- othello
- Orcs
- Octavian
- Otto octavious
- octoman
- Oracle
- Oberon
- oswald cobblepot
- Ophelia
- Obadiah Stane
- Oswald
- Omega red
- Oman
- Odd Job
- orange
- Onslaught
- Oddjob
- O'hare
- octo octavius
- Octopus Doctor
- Obliterator
- Oogie Boogie
- Oger
- Orange man
- Octavio
- Oculus
- Ogres
- octavia
- octopus, dr.
- oedipus
- Orson
- Octavios
- Omicron
- ozzy
- octupus
- oliver twist
- Advertisement
- Ocean
- orpheus
- Oli London
- ock
- Omarosa
- owen
- Octane
- OSCAR
- Oc, Doc
- Octavias
- olive
- Ohio
- orson welles
- Ogar
- Ostrich
- Opal
- Oswald, Lee Harvey
- Oni
- Octopi
- Outsider
- odile
- Orangutan man
- orlando
- Otello
- Ock, Doc
- Ozark
- Orochi
- Owlman
- Opps
- Oddball
- Osbourne
- Ork
- Om puri
- Outlander
- Orca
- Octopus Dr.
- Oh no
- Omkara
- Oligarchs
- oclin
The words in the list Villain with O come from players of the word game Categories game.