Villain with O
- Ogre
- Otto Octavius
- Octavious
- Osama bin laden
- Octavius
- Odin
- Overlord
- Omniman
- Omega
- Oblivion
- Orochimaru
- onceler
- Ozymandias
- Otto
- Omni man
- OJ Simpson
- Orion
- Otto octavious
- osborn
- Orc
- Osborne
- Oliver
- Obito
- Ozai
- Osama
- othello
- octoman
- Octavian
- Orcs
- Oracle
- oswald cobblepot
- Ophelia
- Oberon
- Omega red
- Obadiah Stane
- orange
- Oman
- O'hare
- Orange man
- Oogie Boogie
- Ogres
- Oger
- Octavio
- Obliterator
- Orson
- Onslaught
- Om puri
- Omicron
- oedipus
- Odd Job
- Oculus
- Octavios
- octavia
- ozzy
- Owlman
- owen
- OSCAR
- orpheus
- Omarosa
- oliver twist
- Oli London
- Oddjob
- octupus
- octo octavius
- Octavias
- Octane
- ock
- Ocean
- Ostrich
- Octopus Doctor
The words in the list Villain with O come from players of the word game Categories game.