Villain with O
- Ogre
- Otto Octavius
- Octavious
- Osama bin laden
- Octavius
- Overlord
- Odin
- Omniman
- Omega
- Oblivion
- Orochimaru
- OJ Simpson
- Ozymandias
- onceler
- Omni man
- Orion
- Otto
- osborn
- Otto octavious
- Orc
- Oliver
- Obito
- Osborne
- Orcs
- Ozai
- Osama
- othello
- Octavian
- Oracle
- octoman
- oswald cobblepot
- Ophelia
- Oberon
- Obadiah Stane
- Onslaught
- Odd Job
- Omega red
- O'hare
- Oman
- orange
- Oddjob
- octo octavius
- Obliterator
- Octopus Doctor
- Orange man
- Oger
- Oogie Boogie
- Octavio
- Ogres
- octavia
- Octavios
- Omicron
- oedipus
- Oculus
- Om puri
- Orson
- Octavias
- oliver twist
- Octane
- Owlman
- octupus
- OSCAR
- orpheus
- ock
- Ocean
- Oli London
- Omarosa
- owen
- ozzy
- Otto Von Bismark
- Ozark
- Outlander
- Opal
- Orca
- Orochi
- Ork
- Ogar
- Oni
- Octopi
- Opps
- Otto Octavias
- Outsider
- Ostrich
- Otello
- orlando
- Orangutan man
- orson welles
- odile
- Ohio
- Owl man
- Oddball
- olive
- Osbourne
- Ollie
- Ojoker
- Oh no
- Omkara
- oclin
- Oligarchs
- Otters
The words in the list Villain with O come from players of the word game Categories game.